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Flindof 200mg (30pcs Box)
Flindof (Doxofylline 200mg) is used for the treatment of:
- Bronchial asthma
- Bronchospasm
- Chronic Obstructive Pulmonary Disease (COPD)
- Respiratory diseases with a spastic bronchial component
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✅ Description:
Flindof contains Doxophylline, a novel xanthine bronchodilator that:
- Relaxes bronchial smooth muscle by selectively inhibiting phosphodiesterase-4 (PDE4)
- Differs structurally from theophylline, with a dioxolane group, leading to reduced affinity for adenosine A1 and A2 receptors—resulting in a better safety profile
- Inhibits leukotriene production and platelet activating factor (PAF)
Always follow physician's guidance for dose adjustment.
Contraindications
Precautions & Warnings
Side Effects
Overdose Symptoms:
Severe arrhythmias, tonic-clonic seizures
Requires immediate discontinuation and symptomatic treatment
Pregnancy & Lactation
Driving & Machinery Use
Storage
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Common side effects may include:
- Nausea, vomiting, abdominal pain
- Headache, insomnia, irritability
- Tachycardia, extrasystoles, rapid breathing
- Rare: Hyperglycemia, albuminuria
✔️ Dosage & Administration
Adults:
400 mg tablet 2–3 times daily or as directed by a physician
Elderly:
200 mg tablet 2–3 times daily
Children:
>12 years: 10 ml syrup or 200 mg tablet 2–3 times daily
6–12 years: 6–9 mg/kg body weight, twice daily
Example: A 10 kg child receives 3 ml (60 mg) twice daily
If 400 mg/day is required, a sustained-release (SR) tablet may be taken once daily
✔️ Interaction
- Do not use with other xanthine drugs
- Limit intake of caffeine-containing foods/drinks
- Use caution when taken with sympathomimetics like ephedrine
- Drug interactions that may increase plasma concentration:
- Erythromycin, TAO, clindamycin, allopurinol, cimetidine, propranolol, influenza vaccine
- Drugs like phenytoin or smoking may reduce effectiveness
✔️ Contraindications:
- Known allergy to Doxophylline or other xanthine derivatives
- Acute myocardial infarction, hypotension
- Breastfeeding (contraindicated during lactation)
✔️ Pregnancy & Lactation
- Animal studies show no harmful effects on pre- and postnatal growth
- Use during pregnancy should be based on a risk-benefit assessment
- Contraindicated during breastfeeding
✔️ Use with caution in patients with:
- Heart disease, hypertension
- Elderly, severe hypoxemia, hyperthyroidism, congestive heart failure
- Liver or renal impairment, peptic ulcer
- Conditions like liver disease, infections, or co-administration with specific drugs may increase plasma levels—monitor blood levels if necessary
- No risk of addiction or dependence has been reported
✔️ Storage:
- Store in a cool, dry place, away from heat and direct sunlight
- Keep out of reach of children
- To be used only under prescription by a registered physician
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
